D-ribose (C₅H₁₀O₅)

D-ribose (C₅H₁₀O₅)

The open-chain version of ribose, which occurs naturally in nucleic acids, coenzymes, nucleotides and nucleosides.



D-ribose, monosaccharide, carbohydrate, sugar, simple sugar, aldose, aldopentose, pentose, open chain, nucleic acid, RNA, organic chemistry, chemistry

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D-ribose C₅H₁₀O₅


Molar mass: 150.13 g/mol

Melting point: 95 °C


D-ribose is a colourless, odourless crystalline compound that dissolves well in water, but less well in alcohol. It is an aldopentose. When we dissolve crystalline ribose in water, some of the cyclic molecules open up and transform into open-chain molecules. In its aqueous solution about 8% of the the balanced mixture is made up of open-chain molecules.

The ’D’ means that the chiral centre farther from the oxo group has the same configuration as in D-glyceraldehyde.

Occurrence, production

Cyclic D-ribose occurs in all living organisms as the carbohydrate component of ribonucleic acid, that is, RNA. The sugar-phosphate backbone of the RNA consists of ribose and phosphate molecules. Nitrogen-containing organic bases, which encode the amino acid sequence of proteins are attached to the ribose molecules. It is also found in nucleotide coenzymes such as NAD, NADP and ATP.



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Beta-D-ribose (C₅H₁₀O₅)

A crystalline compound found in nucleic acids, coenzymes, nucleotides and nucleosides.


A polynucleotid made up of phosphoric acid, ribose, and nucleobases (cytosine, uracil, adenine and guanine).

2-deoxy-beta-D-ribose (C₅H₁₀O₄)

A component of DNA, it contains one less hydroxyl group than β-D-ribose.


ATP is the main source of energy for cells.


NAD⁺ is a coenzyme that plays an important role mainly in catabolic processes, while NADP is important in anabolic processes as hydrogen carriers.

Molecule exercise VI (Carbohydrates)

An exercise about the groups and structure of mono-, di- and polysaccharides.

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